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Search Results for " wound healing "

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天然化合物

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カタログ番号	製品名	別名	ターゲット
T21632	Myoseverin		Others , Microtubule Associated
	Myoseverin, an inducer of the reversible fission of multinucleated myotubes into mononucleated fragments, affecting the expression of a variety of growth factor, immunomodulatory, extracellular matrix-remodeling, and str...		Others , Microtubule Associated
T8575	ENFENAMIC ACID		Platelet aggregation
	Enfenamic acid is a platelet aggregation inhibitor and with antirheumatic.		Platelet aggregation
T16850	SB-265610	GSK-CXCR2	CXCR
	SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis (IC50s: 3.7 nM and...		CXCR
T21653	1,4-DPCA		HIF/HIF Prolyl-Hydroxylase
	1,4-DPCA is an inhibitor of prolyl-hydroxylase with an IC50 of 2.4 µM for collagen hydroxylation in human foreskin fibroblasts and 60 μM for factor inhibiting HIF (FIH).		HIF/HIF Prolyl-Hydroxylase
T4478	CID 16020046	C390-0219	Cannabinoid Receptor
	CID 16020046 (C390-0219) is a selective GPR55 antagonist, inhibiting GPR55 constitutive activity with IC50 of 0.15 μM in yeast.		Cannabinoid Receptor
T2206	Quadrol	N,N,N′,N′-Tetrakis(2-hydroxypropyl)ethylenediamine,EDTP,Edetol	Others
	Quadrol (EDTP) is an immunostimulant, accelerated wound healing.		Others
T19841	Tribenoside	Glyvenol,Glyvenal,Ba 2140,BG-356,Glivenol,TBGF	Others
	Tribenoside (BG-356) is a vasoprotectant with mild anti-inflammatory, analgesic, and wound healing properties.		Others
T40570L	LKKTETQ acetate	LKKTETQ acetate (476014-70-7 Free base)	Others
	LKKTETQ acetate is the active site in the protein thymosin β4 responsible for wound healing, actin binding and cell migration.		Others
T13823	Polyvinylpyrrolidone	PVP,Povidone,Polyvidone	Others
	Polyvinylpyrrolidone (Polyvidone) used in human and veterinary medicine as an effective wound healing accelerator.		Others
T41206	Poly Vinyl Alcohol	Polyvinyl alcohol	Others
	Poly Vinyl Alcohol (Polyvinyl alcohol) is a water-soluble, biodegradable, wound-healing polymer used in a wide range of biomedical applications.Poly Vinyl Alcohol is commonly used in the manufacture of medical excipients...		Others
T74048	PAPA NONOate		Endogenous Metabolite , NO Synthase
	PAPA NONOate is a pH-regulated NO donor.PAPA NONOate has potential antitumor activity and can be used to study diabetic wound healing disorders.		Endogenous Metabolite , NO Synthase
T7116	Sodium gualenate	Guaiazulenesulfonate sodium	Others
	Sodium gualenate (Guaiazulenesulfonate sodium) (Guaiazulenesulfonate sodium), a hydrophilic derivative of guaiazulene (GA), is an unstable compound. It has anti-inflammatory and wound-healing effects.		Others
TP2319	Thymosin β4 acetate(75591-33-4 free base)		Autophagy
	Thymosin β4 (Tβ4) is a thymic hormone with multiple and different intracellular and extracellular activities affecting wound healing, inflammation, fibrosis and tissue regeneration.		Autophagy
T21550	Blebbistatin	(±)-Blebbistatin	ATPase , Myosin
	Blebbistatin ((±)-Blebbistatin) is a selective non-muscle myosin II (NMII) inhibitor. It promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing. Furthermore it preserves cell jun...		ATPase , Myosin
T32613	LCB 03-0110 dihydrochloride		Src
	LCB 03-0110 Dihydrochloride is a potent inhibitor of the c-Src kinase (IC50 = 1.3 nM) and tyrosine kinases in the BTK and SYK family, as well as in the DDR2 family. It inhibits LPS-induced activation of macrophages and T...		Src
T4425	JK-P3		VEGFR
	JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube format...		VEGFR
T41231	GP 1a		Cannabinoid Receptor , PERK , Arrestin
	GP 1a is a potent agonist of cannabinoid receptor 2 (CB2) (EC50=7.1), as shown in cAMP, GTPγS and β-arrestin recruitment assays. GP 1a is approximately 30-fold more selective for CB2 receptors than CB1 receptors and incr...		Cannabinoid Receptor , PERK , Arrestin
T29547	Acemannan	Acemannanan
	Acemannan can produce cell proliferation and skin wound healing through AKT/mTOR signaling pathway.
T28146	ND-336	ND336,ND-336 hydrochloride,ND 336
	ND-336 is a highly selective inhibitor ofMMP-2, MMP-9 and MMP-14. ND-336 accelerates diabetic wound healing by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound.
T34693	Sphingosine phosphorylcholine
	Sphingosine phosphorylcholine is a wound healing agent.
T25309	Dermabond	Liquid Bandage,2-Octyl 2-cyanoacrylate,RiteLok CON 895
	Dermabond is an antibacterial compound that has been used in basic science research for wound healing.
T40570	LKKTETQ
	LKKTETQ, a peptide segment within thymosin β 4, constitutes the protein's active site responsible for actin binding, cell migration, and wound healing.
T30107	Apratyramide
	Apratyramide is a marine-derived peptidic stimulator of VEGF-A and other growth factors with potential application in wound healing.
T70826	PF-03671148
	PF-03671148 is a potent ALK inhibitor. PF-03671148 inhibits the expression of fibrotic genes and protein markers both in vitro in human fibroblasts and in vivo in a rat wound repair model. Wound healing is not inhibited ...
T21185	CEP03	CEP 03,CEP-03
	CEP03 enhances EC/EPC proliferation, tubelike formation, and wound-healing efficiency, leading to promote angiogenesis and significantly improve blood flow perfusion recovery in the ischemic hind limbs of mice.
T34653	SK1071
	SK1071 is a novel migrastatin analogs, which demonstrated improved performance over migrastatin, with nanomolar IC50 values in chamber cell migration assays with tumor cells and human umbilical vein endothelial cells (HU...
T41189	AY 254
	AY 254 is a potent PAR2 biased agonist. Selectively activates ERK1/2 signaling (EC50= 2 nM for ERK1/2 phosphorylation versus 80 nM for Ca2+release). Reduces cytoKi ne-induced caspase 3/8 activation, promotes scratch-woun...
T81330	Q-Peptide
	Q-Peptide, an angiopoietin-1 derived peptide (QHREDGS), enhances keratinocyte migration, thereby facilitating wound healing in a diabetic mouse model, and accelerates wound closure [1].
T14139	Aganepag	AGN 210937	Prostaglandin Receptor
	Aganepag, a potent Prostanoid EP2 receptor agonist, exhibits remarkable selectivity with an EC50 of 0.19 nM, demonstrating no activity at the EP4 receptor. Its applications are primarily in the fields of wound healing, s...		Prostaglandin Receptor
T82358	G-{d-Arg}-GDSPASSK
	G-{d-Arg}-GDSPASSK is a polypeptide that inhibits cell adhesion, facilitates wound healing, and promotes tissue repair [1].
T61106	GRP78-IN-1
	GRP78-IN-1 displays interactions with specific residues on the GRP78 protein with a binding energy of -8.07 kcal/mol. This compound possesses potent cytotoxic and anti-proliferative effects on cancer cells, particularly ...
T81404	Prezatide copper	Bisprezatide copper,PC 1020,Iamin
	Prezatide copper (also known as Bisprezatide copper or Iamin) serves as an inhibitor of hair loss and is recognized for its multiple wound-healing properties as a human growth factor [1].
T36080	Rivenprost	ONO-4819
	Prostaglandin E2 activates four distinct G protein-coupled receptors, EP1-4. Rivenprost is a potent and selective agonist for the EP4 receptor (Ki = 0.7, 56, 620, and >10,000 nM for EP4, EP3, EP2, and EP1, respectively)....
T75858	LL-37, human acetate
	LL-37, human acetate, is a 37-residue amphipathic peptide derived from cathelicidin, known for its broad-spectrum antimicrobial properties. This compound not only plays a crucial role in safeguarding the cornea against i...
T75857	LL-37, human TFA
	LL-37, human TFA, is a cathelicidin-derived, 37-residue, amphipathic antimicrobial peptide that displays a broad spectrum of antimicrobial activity. It may protect the cornea from infection and modulate wound healing [1]...
T35408	(±)10(11)-EDP Ethanolamide
	(±)10(11)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 0.43 and 22.5 nM for CB1 and CB2 receptors, respectively). It is produced though direct epoxygenation of docosah...
T78018	Plasminogen
	Plasminogen is a zymogen secreted as a precursor protein that, when cleaved by urokinase plasminogen activator (uPA) or tissue plasminogen activator (tPA), is converted into plasmin. Plasmin is a protease with broad spec...
T74212	BLT2 probe 1		Leukotriene Receptor
	BLT2 Probe 1 (Compound 13), a fluorescent probe derived from the synthetic BLT2 agonist CAY10583, offers a robust tool for exploring BLT2 receptor ligand pharmacology across various assay systems [1]. As BLT2 is a valuab...		Leukotriene Receptor
T80859	Vitronectin
	Vitronectin, a multifunctional glycoprotein found in blood and the extracellular matrix, interacts with glycosaminoglycans, collagen, plasminogen, and the urokinase-receptor, in addition to stabilizing the inhibitory con...
T81396	PRO-F
	PRO-F, a photoactivable hydrogen sulfide (H2S) donor, possesses reactive oxygen species (ROS) scavenging properties and emits a fluorescent signal upon light activation, enabling real-time tracking of H2S release. Its ac...
T79798	PHD-IN-2		HIF/HIF Prolyl-Hydroxylase
	PHD-IN-2 (Compound 91), a potent PHD antagonist with an IC50 of less than 5 nM, effectively stimulates erythropoietin synthesis in HEP3B cells with an EC50 of less than 2.5 μM. It is applicable for research purposes acro...		HIF/HIF Prolyl-Hydroxylase
T35616	Migrastatin
	Migrastatin is a bacterial metabolite that has been found inStreptomyceswith antimuscarinic and anticancer activities.1,2It binds to M1-5muscarinic acetylcholine receptors (Kis = >200, 200, 31, 43, and >200 μM, respectiv...
T82151	Hyaluronan-binding peptide, biotin labeled
	Biotin-labeled Hyaluronan-binding Peptide is a biologically active peptide conjugated with biotin via a C-terminal GGGSK linker. It interacts with the non-sulfated glycosaminoglycan hyaluronan (HA), prominent in the extr...
T35671	Salazinic Acid
	Salazinic acid is a depsidone lichen metabolite that has been found in P. sulcata.1 It is active against B. cereus, B. subtilis, S. aureus, P. aeruginosa, S. typhimurium, C. albicans, and A. niger in vitro (MICs = 3.9-30...
T83874	S-72
	S-72 acts as a microtubule polymerization inhibitor, effective in cell-free assays at concentrations of 1, 3, and 10 µM. At nanomolar levels (IC50s = 15.64 and 26.32 nM, respectively), it diminishes the viability of both...
T83898	S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine	SFN-Cys,D,L-Sulforaphane-L-cysteine
	S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine (SFN-Cys) is an isothiocyanate derivative, functioning as an active metabolite of sulforaphane, a class I and II histone deacetylase (HDAC) inhibitor, and anticancer agen...
T64692	AMY-101 acetate
	Complement component C3 plays a particularly versatile role in this process by keeping the cascade alert, acting as a point of convergence of activation pathways, fueling the amplification of the complement response, exe...

Compounds

Myoseverin

T21632

Synonym:

Target: Others, Microtubule Associated

ENFENAMIC ACID

T8575

Synonym:

Target: Platelet aggregation

Target: HIF/HIF Prolyl-Hydroxylase

CID 16020046

T4478

Synonym: C390-0219

Target: Cannabinoid Receptor

Quadrol

T2206

Synonym: N,N,N′,N′-Tetrakis(2-hydroxypropyl)ethylenediamine,EDTP,Edetol

Target: Others

Tribenoside

T19841

Synonym: Glyvenol,Glyvenal,Ba 2140,BG-356,Glivenol,TBGF

Target: Others

LKKTETQ acetate

T40570L

Synonym: LKKTETQ acetate (476014-70-7 Free base)

Target: Others

Polyvinylpyrrolidone

T13823

Synonym: PVP,Povidone,Polyvidone

Target: Others

Poly Vinyl Alcohol

T41206

Synonym: Polyvinyl alcohol

Target: Endogenous Metabolite, NO Synthase

Sodium gualenate

T7116

Synonym: Guaiazulenesulfonate sodium

Target: Others

Thymosin β4 acetate(75591-33-4 free base)

Synonym: (±)-Blebbistatin

Target: ATPase, Myosin

LCB 03-0110 dihydrochloride

Target: Cannabinoid Receptor, PERK, Arrestin

Synonym: ND336,ND-336 hydrochloride,ND 336

Target:

Sphingosine phosphorylcholine

Synonym: Liquid Bandage,2-Octyl 2-cyanoacrylate,RiteLok CON 895

Synonym: CEP 03,CEP-03

Target: Prostaglandin Receptor

Synonym: Bisprezatide copper,PC 1020,Iamin

(±)10(11)-EDP Ethanolamide

Target: Leukotriene Receptor

Target: HIF/HIF Prolyl-Hydroxylase

Hyaluronan-binding peptide, biotin labeled

S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine

T83898

Synonym: SFN-Cys,D,L-Sulforaphane-L-cysteine

カタログ番号	製品名	別名	ターゲット
T3855	Tracheloside		Estrogen Receptor/ERR , Phosphorylase
	Tracheloside significantly decreases the activity of alkaline phosphatase (IC50: 0.31 μg/ml), a level of inhibition comparable to that of tamoxifen (IC50: 0.43 μg/ml).		Estrogen Receptor/ERR , Phosphorylase
T3881	Vaccarin		Integrin , Akt , PERK , AMPK
	Vaccarin is a major flavonoid glycoside in Vaccariae semen, its biotransformation pathways involves methylation, hydroxylation, glycosylation and deglycosylation.		Integrin , Akt , PERK , AMPK
T5S1982	Periplocin	Periplocoside	Apoptosis , Others
	1. Periplocin (Periplocoside) has anti-cancer effects on lung cancer cells, induces apoptosis and inhibits growth of cancer cells by the beta-catenin/Tcf signaling pathway. 2. Periplocin is used for treatment of rheumato...		Apoptosis , Others
TN1686	Ginsenoside Rg4		Antibacterial
	Ginsenoside Rg4 is a natural product		Antibacterial
T2827	Asiatic acid	Asiantic acid,Dammarolic acid	Apoptosis , p38 MAPK , Parasite
	Asiatic acid (Dammarolic acid) is the aglycone of asiaticoside used in wound healing with antioxidant, anti-inflammatory, and neuroprotective properties.		Apoptosis , p38 MAPK , Parasite
TN3016	4',6,7-Trimethoxyisoflavone		MMP
	4',6,7-Trimethoxyisoflavone promotes wound healing through NOX2 induction, which leads to collective migration and MMP activation.		MMP
TN2077	(+/-)-Pinocembrin	NSC 43318,(±)-5,7-Dihydroxyflavanone	GPR , Others
	(+/-)-Pinocembrin (NSC-43318), a natural product from axillary pines, is a GPR120 ligand that promotes wound healing in the HaCaT cell line.		GPR , Others
T4454	Traumatic Acid	Dodec-2-Enedioic Acid,2E-Dodecenedioic Acid,Trans-2-Dodecenedioic Acid	Antioxidant
	Traumatic Acid (Dodec-2-Enedioic Acid) is a product of the hydroperoxide lyase pathway in plants. Potential as a wound healing agent that stimulates cell division near a wound site to form a protective callus.		Antioxidant
TN1079	Deoxyelephantopin		NF-κB
	Deoxyelephantopin has anti-inflammatory, hepatoprotective, and wound healing activities; it also has antitumor activity.Deoxyelephantopin inhibits NF-κB, MAPK, PI3K/Akt, and β-catenin signaling		NF-κB
T1125	Shikonin	NSC 252844,Isoarnebin 4,(+)-Shikonin,Alkanna Red,C.I. 75535,Anchusa acid	TNF , NF-κB , Chloride channel , HIV Protease , PKM
	Shikonin (Anchusa acid) is a natural product, a TMEM16A chloride channel inhibitor (IC50=6.5 μM) and selective PKM2 inhibitor. Shikonin exhibits antitumor, anti-inflammatory and wound healing activities.		TNF , NF-κB , Chloride channel , HIV Protease , PKM
TN7082	Demethyldaphnoretin-7-O-glucoside		Others
	Demethyldaphnoretin-7-O-glucoside is a natural product that is isolated from Daphne oleoides Schreber subsp. kurdica (DOK). In Turkish traditional medicine, the aerial parts of DOK have been used to treat malaria, rheuma...		Others
TN1641	(-)-Fenchone		Others , Antioxidant , Antifungal
	(-)-Fenchone is a bicyclic monoterpenoid widely distributed in plants and can be extracted from Foeniculum vulgare and Peumus boldus. (-)-Fenchone has a wide range of biological activities including antioxidant, wound he...		Others , Antioxidant , Antifungal
TN6926	Paeonoside		Others
	Paeonoside, found in P. suffruticosa, is biologically active and can promote wound healing and migration during osteoblast differentiation. Paeonoside has certain antidiabetic activity and may prevent sepsis and death fr...		Others
TN1132	Procyanidin A2		IL Receptor , TNF , transporter , Antibacterial
	Procyanidin A2 is a potential precursor of 5-(3',4'-dihydroxyphenyl)-γ-valerolactone, exhibits antioxidant, anti-inflammary, anti-hyperglycemia, and anti-type 2 diabetes activities. Procyanidin A2 demonstrates liver cell...		IL Receptor , TNF , transporter , Antibacterial
T3O2749	L-Leucine	(S)-Leucine,Leu	mTOR
	L-Leucine ((S)-Leucine) is one of nine essential amino acids in humans (provided by food), L-Leucine is important for protein synthesis and many metabolic functions. L-Leucine contributes to regulation of blood-sugar lev...		mTOR
T5S2347	Deoxyshikonin	Arnebin 7	Others , HIF/HIF Prolyl-Hydroxylase , Antibacterial
	1. Deoxyshikonin (Arnebin 7) may be a new drug candidate for wound healing and treatment of lymphatic diseases. 2. Deoxyshikonin enhances the ability of human dermal lymphatic microvascular endothelial cells (HMVEC-dLy) ...		Others , HIF/HIF Prolyl-Hydroxylase , Antibacterial
TN6872	Trypsin		Protease-activated Receptor
	Trypsin is a serine protease that can be isolated from fish to hydrolyze lysine or arginine carboxy-side proteins. With the anti-inflammatory activity, Trypsin could induce the cell membrane fusion of PDCoV-infected cell...		Protease-activated Receptor
TN6495	3,4-O-dimethylcedrusin
	3′,4-O-Dimethylcedrusin can improve wound healing in vivo by stimulating the formation of fibroblasts and collagen.
T13559	Astragaloside VI		EGFR
			EGFR
TN5044	Specioside		Others
	Specioside has antioxidant, analgesic, anti-dyspeptic, astringent, liver stimulating and wound healing activities. It ameliorates oxidative stress and promotes longevity in Caenorhabditis elegans.		Others
T81322	Quercetin-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside
	Quercetin-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside, isolated from the aerial parts of the fern Ophioglossum vulgatum L., exhibits wound healing activity [1].
T78490	Polygalacturonic acid	Galacturonic acid polymer
	Polygalacturonic acid (Galacturonic acid polymer), a transparent colloid, constitutes a significant portion of the cell wall. It is employed in the synthesis of silver nanoparticles (AgNPs), serving both as an antioxidan...

天然物製品

Tracheloside

T3855

Synonym:

Target: Estrogen Receptor/ERR, Phosphorylase

Vaccarin

T3881

Synonym:

Target: Integrin, Akt, PERK, AMPK

Periplocin

T5S1982

Synonym: Periplocoside

Target: Apoptosis, Others

Ginsenoside Rg4

TN1686

Synonym:

Target: Antibacterial

Asiatic acid

T2827

Synonym: Asiantic acid,Dammarolic acid

Target: Apoptosis, p38 MAPK, Parasite

4',6,7-Trimethoxyisoflavone

Synonym: NSC 43318,(±)-5,7-Dihydroxyflavanone

Target: GPR, Others

Traumatic Acid

T4454

Synonym: Dodec-2-Enedioic Acid,2E-Dodecenedioic Acid,Trans-2-Dodecenedioic Acid

Synonym: NSC 252844,Isoarnebin 4,(+)-Shikonin,Alkanna Red,C.I. 75535,Anchusa acid

Target: TNF, NF-κB, Chloride channel, HIV Protease, PKM

demethyldaphnoretin-7-O-glucoside

Target: Others, Antioxidant, Antifungal

Target: IL Receptor, TNF, transporter, Antibacterial

L-Leucine

T3O2749

Synonym: (S)-Leucine,Leu

Target: Others, HIF/HIF Prolyl-Hydroxylase, Antibacterial

Trypsin

TN6872

Synonym:

Target: Protease-activated Receptor

3,4-O-dimethylcedrusin

Quercetin-3-O-[(6-caffeoyl)-β-glucopyranosyl (1→3) α-rhamnopyranoside]-7-O-α-rhamnopyranoside

T81322

Synonym:

Target:

Polygalacturonic acid

T78490

Synonym: Galacturonic acid polymer

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-02185	Coagulation factor XIII B/F13B Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Coagulation factor XIII B chain, also known as Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain and F13B, is a secreted protein which contains 1 Sushi ...
TMPJ-00562	PDGF-BB Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (P...
TMPJ-00037	FGF-2 Protein, Mouse, Recombinant	Mouse	E. coli
	FGF basic is one of 22 mitogenic proteins of the FGF family, which show 35-60% amino acid conservation. Unlike other FGFs, FGF acidic and basic lack signal peptides and are secreted by an alternate pathway. The 17 kDa mo...
TMPY-01061	FGF-10 Protein, Human, Recombinant	Human	E. coli
	Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes...
TMPH-02830	PLET1 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle.
TMPH-02831	PLET1 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle.
TMPH-01865	PLET1 Protein, Human, Recombinant (His)	Human	E. coli
	Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle. PLET1...
TMPH-02594	MMP-13 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the hig...
TMPH-01866	PLET1 Protein, Human, Recombinant (His & Myc)	Human	Baculovirus Insect Cells
	Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle. PLET1...
TMPK-00367	MMP-9 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demon...
TMPK-00503	MMP-9 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demon...
TMPK-01334	EMMPRIN/CD147 Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
	CD147, also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulation of extracellular matrix (ECM) remodeling during physiolo...
TMPH-01297	DDR1 Protein, Human, Recombinant (aa 21-417, His)	Human	HEK293 Cells
	Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival ...
TMPH-01974	Prothrombin Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wo...
TMPK-00368	MMP-9 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demon...
TMPJ-00271	SMAD3 Protein, Human, Recombinant (His & Flag)	Human	E. coli
	Mothers against decapentaplegic homolog 3(SMAD3) is a cytoplasm protein which belongs to the dwarfin/SMAD family. Smad proteins undergo rapid nuclear translocation upon stimulation by transforming growth factor and in so...
TMPH-03599	Streptopain Protein, S. pyogenes, Recombinant (His & SUMO)	Streptococcus pyogenes	E. coli
	Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelia...
TMPH-03598	Streptopain Protein, S. pyogenes serotype M28, Recombinant (His & SUMO)	Streptococcus pyogenes	E. coli
	Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelia...
TMPK-01044	VEGFC Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	the lymphangiogenic factors vascular endothelial growth factor C (VEGFC) and VEGFD are cleaved by thrombin and plasmin, serine proteases generated during hemostasis and wound healing. Genetic studies reveal that platelet...
TMPY-04801	Fibromodulin Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Fibromodulin (FMOD), an ECM small leucine-rich proteoglycan (SLRP), was reported to promote angiogenesis not only during wound healing, but also in optical and cutaneous angiogenesis-dependent diseases. The autocrine FM...
TMPH-02835	PDGFD Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role ...
TMPK-01043	VEGFC Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	the lymphangiogenic factors vascular endothelial growth factor C (VEGFC) and VEGFD are cleaved by thrombin and plasmin, serine proteases generated during hemostasis and wound healing. Genetic studies reveal that platelet...
TMPY-02838	FGFBP3 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	FGFBP3 is a member of the fibroblast growth factor-binding protein family. Members of this family binds and activates FGF-1 and FGF-2, thereby contributing to tumor angiogenesis. Fibroblast growth factors (FGFs) are impo...
TMPJ-00771	TGF beta 1 Protein, Mouse/Rat, Recombinant	Mouse,Rat	HEK293 Cells
	Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differen...
TMPJ-01433	Fibronectin Protein, Human, Recombinant (ED-B domain, Avi & His), Biotinylated	Human	E. coli
	Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components ...
TMPY-00371	STC1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Stanniocalcin-1 (STC1) is a paracrine factor associated with inflammation and carcinogenesis. STC1 is a secreted glycoprotein hormone and involved in various types of human malignancies. Stanniocalcin-1 (STC1), which has...
TMPY-01190	INHBB Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two ...
TMPY-01846	Activin A Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two ...
TMPJ-00304	ALK-1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-β superfamily of ligands, which mediates signaling of BMP9 (bone morphogenetic protein) and BMP10. ALK1 signaling is necessary for angi...
TMPY-01484	THSD1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Thrombospondin type-1 domain-containing protein 1, also known as transmembrane molecule with thrombospondin module, THSD1 and TMTSP, is a single-pass type I membrane protein that contains one TSP type-1 domain. THSD1 is ...
TMPY-03419	SMAD3 Protein, Human, Mouse, Rat, Recombinant (His & GST)	Human,Mouse,Rat	Baculovirus Insect Cells
	SMAD3 belongs to the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD3 is...
TMPJ-00534	HFcgR4 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Fcgr4, also known as CD16-2, is one of the receptors for Fc region of IgG which involve in immune responses. Fcgr4 mainly functions in cellular response to lipopolysaccharide, NK T cell proliferation, regulation of senso...
TMPJ-01177	NOV/CCN3 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	NOV, also called CCN3, is a secreted protein of CCN family members. CCN family members are highly conserved cysteine rich proteins sharing a common modular structure having 4 conserved domains, insulin-like growth factor...
TMPY-02174	FABP5 Protein, Human, Recombinant	Human	E. coli
	Fatty acid-binding protein, also known as Epidermal-type fatty acid-binding protein, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog, E-FABP and FABP5, is a cytoplasm protein whic...
TMPJ-00535	F13A Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, ...
TMPY-01680	Lumican Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Lumican, a prototypic leucine-rich proteoglycan with keratan sulfate side chains, is a major component of the cornea, dermal, and muscle connective tissues. In these bifunctional molecules, the protein moiety binds colla...
TMPY-02760	CALML3 Protein, Human, Recombinant (His)	Human	E. coli
	Calmodulin-like protein 3 (CALML3) is similar to that of authentic calmodulin and may actually compete with calmodulin by binding, with different affinity, to cellular substrates. Calmodulin-like protein 3 (CALML3) is a ...
TMPY-02246	HB-EGF Protein, Human, Recombinant	Human	Baculovirus Insect Cells
	Heparin-binding EGF-like growth factor (HBEGF), a member of the EGF family of growth factors, exerts its biological activity through activation of the EGFR and other ErbB receptors. Soluble mature HBEGF is proteolyticall...
TMPH-02524	Arginase-1/ARG1 Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell ...
TMPH-03753	MYLK Protein, Human, Recombinant (His)	Human	E. coli
	Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activity. Phos...
TMPY-01212	ADAM12 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	The ADAMs (a disintegrin and metalloprotease) comprise a family of multidomain proteins with metalloprotease, cell adhesion, and signaling activities. Human ADAM12, which is implicated in diseases such as cancer, is expr...

Coagulation factor XIII B/F13B Protein, Human, Recombinant (His)

TMPY-02185

Species: Human

Expression System: HEK293 Cells

PDGF-BB Protein, Mouse, Recombinant (His)

TMPJ-00562

Species: Mouse

Expression System: E. coli

FGF-2 Protein, Mouse, Recombinant

TMPJ-00037

Species: Mouse

Expression System: E. coli

FGF-10 Protein, Human, Recombinant

TMPY-01061

Species: Human

Expression System: E. coli

PLET1 Protein, Mouse, Recombinant (His)

TMPH-02830

Species: Mouse

Expression System: Baculovirus Insect Cells

PLET1 Protein, Mouse, Recombinant (His & SUMO)

TMPH-02831

Species: Mouse

Expression System: E. coli

PLET1 Protein, Human, Recombinant (His)

TMPH-01865

Species: Human

Expression System: E. coli

MMP-13 Protein, Mouse, Recombinant (His)

TMPH-02594

Species: Mouse

Expression System: E. coli

PLET1 Protein, Human, Recombinant (His & Myc)

TMPH-01866

Species: Human

Expression System: Baculovirus Insect Cells

MMP-9 Protein, Human, Recombinant (His & Avi)

TMPK-00367

Species: Human

Expression System: HEK293 Cells

MMP-9 Protein, Cynomolgus, Recombinant (His)

TMPK-00503

Species: Cynomolgus

Expression System: HEK293 Cells

EMMPRIN/CD147 Protein, Canine, Recombinant (His)

TMPK-01334

Species: Canine

Expression System: HEK293 Cells

DDR1 Protein, Human, Recombinant (aa 21-417, His)

TMPH-01297

Species: Human

Expression System: HEK293 Cells

Prothrombin Protein, Human, Recombinant (His)

TMPH-01974

Species: Human

Expression System: P. pastoris (Yeast)

MMP-9 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00368

Species: Human

Expression System: HEK293 Cells

SMAD3 Protein, Human, Recombinant (His & Flag)

TMPJ-00271

Species: Human

Expression System: E. coli

Streptopain Protein, S. pyogenes, Recombinant (His & SUMO)

TMPH-03599

Species: Streptococcus pyogenes

Expression System: E. coli

Streptopain Protein, S. pyogenes serotype M28, Recombinant (His & SUMO)

TMPH-03598

Species: Streptococcus pyogenes

Expression System: E. coli

VEGFC Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-01044

Species: Human

Expression System: HEK293 Cells

Fibromodulin Protein, Human, Recombinant (hFc)

TMPY-04801

Species: Human

Expression System: HEK293 Cells

PDGFD Protein, Mouse, Recombinant (His & SUMO)

TMPH-02835

Species: Mouse

Expression System: E. coli

VEGFC Protein, Human, Recombinant (His & Avi)

TMPK-01043

Species: Human

Expression System: HEK293 Cells

FGFBP3 Protein, Human, Recombinant (His)

TMPY-02838

Species: Human

Expression System: Baculovirus Insect Cells

TGF beta 1 Protein, Mouse/Rat, Recombinant

TMPJ-00771

Species: Mouse,Rat

Expression System: HEK293 Cells

Fibronectin Protein, Human, Recombinant (ED-B domain, Avi & His), Biotinylated

TMPJ-01433

Species: Human

Expression System: E. coli

STC1 Protein, Human, Recombinant (His)

TMPY-00371

Species: Human

Expression System: HEK293 Cells

INHBB Protein, Human, Recombinant (His)

TMPY-01190

Species: Human

Expression System: HEK293 Cells

Activin A Protein, Mouse, Recombinant (His)

TMPY-01846

Species: Mouse

Expression System: HEK293 Cells

ALK-1 Protein, Mouse, Recombinant (hFc)

TMPJ-00304

Species: Mouse

Expression System: HEK293 Cells

THSD1 Protein, Mouse, Recombinant (His)

TMPY-01484

Species: Mouse

Expression System: HEK293 Cells

SMAD3 Protein, Human, Mouse, Rat, Recombinant (His & GST)

TMPY-03419

Species: Human,Mouse,Rat

Expression System: Baculovirus Insect Cells

hFcgR4 Protein, Mouse, Recombinant (His)

TMPJ-00534

Species: Mouse

Expression System: HEK293 Cells

NOV/CCN3 Protein, Mouse, Recombinant (His)

TMPJ-01177

Species: Mouse

Expression System: HEK293 Cells

FABP5 Protein, Human, Recombinant

TMPY-02174

Species: Human

Expression System: E. coli

F13A Protein, Human, Recombinant (His)

TMPJ-00535

Species: Human

Expression System: HEK293 Cells

Lumican Protein, Human, Recombinant (His)

TMPY-01680

Species: Human

Expression System: HEK293 Cells

CALML3 Protein, Human, Recombinant (His)

TMPY-02760

Species: Human

Expression System: E. coli

HB-EGF Protein, Human, Recombinant

TMPY-02246

Species: Human

Expression System: Baculovirus Insect Cells

Arginase-1/ARG1 Protein, Mouse, Recombinant (His)

TMPH-02524

Species: Mouse

Expression System: P. pastoris (Yeast)

MYLK Protein, Human, Recombinant (His)

TMPH-03753

Species: Human

Expression System: E. coli

ADAM12 Protein, Human, Recombinant (His)

TMPY-01212

Species: Human

Expression System: HEK293 Cells

カタログ番号	製品名
L9810	Anti-Fibrosis Compound Library	1180 compounds
	A unique collection of 1180 potential anti-fibrosis compounds, can be used in HTS and HCS;
L4800	Angiogenesis related Compound Library	1353 compounds
	A unique collection of 1353 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS);
L7600	Chemokine Inhibitor Library	59 compounds
	A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening;
L8500	HIF-1 Signaling Pathway Compound Library	1336 compounds
	A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies；

ライブラリー

Anti-Fibrosis Compound Library

L9810

Compounds: 1180

Angiogenesis related Compound Library

L4800

Compounds: 1353

Chemokine Inhibitor Library

L7600

Compounds: 59

HIF-1 Signaling Pathway Compound Library

L8500

Compounds: 1336